The VPA_RAT group exhibited lower species richness than the Control group, evidenced by reduced values in Chao1 (Figure S3A), Faith PD (Figure S3B), and observed features indices (Figure S3C)
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The mechanism in one sentence: hollow gold-plated microneedles at fixed 0.5mm depth create temporary channels through the stratum corneum, the upper epidermis, and into the papillary dermis where fibroblasts live
doi: 10.1007/s00394-015-1104-x