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It is basic thermodynamics meeting evolutionary biology

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10.1111/dom.12932 [DOI] [PMC free article] [PubMed] [Google Scholar] 182.Lean ME, Carraro R, Finer N, Hartvig H, Lindegaard ML, Rssner S, et al

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The missing glucagon component means tirzepatide-based stacks lack the thermogenic and lipolytic advantages that glucagon agonism provides