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This change in shape will affect also the components existing inside the cytoplasm, namely the cytoskeleton, in which keratin fibers are crucial (Ramms et al., 2013)

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[14] ( Figure 1A ) Approved in 2023, tirzepatide (TZP) is a dual GIP/GLP-1 receptor agonist that significantly enhances glycemic control and is under clinical investigation for obesity, cardiovascular disease, and non-alcoholic steatohepatitis

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