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Clinically meaningful responses in insulin-resistant patients typically include a reduction in fasting insulin of 20-40% and an improvement in HOMA-IR within 8-12 weeks at therapeutic doses, though individual variability is wide [1]

Findings: Preclinical models showed decreased fat mass accumulation with peptide administration

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Reacting to our concerns about the alternative oral treatment the new guideline states clearly that if patients experience any neurological symptoms numbness or pins and needles then he or she must contact their GP immediately

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The most common side effects include: Injection site reactions: It is common to experience mild redness, swelling, or itching on the injection site