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Despite their effectiveness, these treatments are accompanied by potential side effects and risks

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Its a choice that reflects a deliberate strategy to achieve a specific pharmacokinetic profile suitable for studying the slow, steady processes of metabolism

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Additionally, this would place intracranial pressure control as one of the mechanisms underlying migraine, a pharmacologically-targetable one. Braca added that they plan to conduct a double-blind randomized placebo-controlled study as this was a pilot, exploratory study