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The findings uncovered that in comparison to the control group, mRNA expression levels of CXCL10 and MMP13 were substantially enhanced in the rheumatoid arthritis synovial fibroblast cells, whereas the mRNA expression of EDNRB was markedly reduced (Figure 12A)

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HepG2 cells were cultured in DMEM supplemented with 10% FBS and 1% penicillin-streptomycin

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