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Alpha-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients

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Gherghel D, Griffiths HR, Hilton EJ, Cunliffe IA

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further reported that poliumoside counteracts HGHF-induced bone degradation and ferroptosis by activating the NRF2/GPX4 signaling pathway, suggesting its potential as a novel therapeutic approach for T2DM-associated osteoporosis [176]