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Semaglutide, by contrast, harnesses the incretin hormone GLP-1 to alter central appetite circuits and peripheral glucose metabolism

NAc, ML: 1.25 mm, AP: +1.0 mm, DV: 4.7 mm from Bregma

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Through intracellular calcium mobilization, phospholipase C, and G_q-protein signaling, this causes a fast GH pulse