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The Institute of Medicine reports that no adverse effects have been associated with excess vitamin B12 intake from food, supplements, or injections in healthy individuals. Nevertheless, its crucial to consult a professional before beginning any high-dosage supplement
**Biotin can interfere with some laboratory testing, this may cause results to be either falsely elevated or decreased
B12 is required for healthy red blood cell production, maintenance of the myelin sheath and metabolizing fatty acids
When it comes to the functioning of your cells, methyl groups are used in methylation reactions.[ref] Examples of methylation reactions include: synthesis of some of the nucleic acid (DNA) bases turning off genes so that they arent transcribed (DNA methylation) converting serotonin into melatonin methylating arsenic so that it can be excreted breaking down neurotransmitters metabolizing estrogen regenerating methionine from homocysteine Methylation in the right amount: For example, you need enough folate (vitamin B9) and methylcobalamin (vitamin B12) for the methionine synthase reaction to occur
Insufficient human clinical trials have led to a lack of data to determine a safe dose