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This particular group of lesions exhibits distinct and, at times, worrisome cytologic and architectural features that separate them from other nevi and are the source of possible diagnostic pitfalls

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2009;198(1):1925 Li, Y., Chang, S.-C., Goldstein, B

Aggressive mixing can damage the molecular structure and reduce potency

Its worth experimenting, carefully, to find what feels best for your body. Also consider seeking help from a GI provider