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Weight loss with low-dose semaglutide typically follows a slower trajectory than higher doses, but the slower pace often correlates with better adherence and fewer gastrointestinal side effects

Binary clinical outcomes, including acute kidney injury, severe hypoglycemia, adverse events leading to treatment discontinuation, and cardiovascular events, were summarized descriptively without formal hypothesis testing, given the absence of a comparator group and limited statistical power

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doi: 10.1016/j.ajo.2004.10.021

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Randomized placebo-controlled trial of reloxaliase in enteric hyperoxaluria