Aging reduces both GAG synthesis and retention capacity
There is a deeper reason too
Cellular Turnover Because the skin you see today will be gone in a month, any internal changes must be maintained to affect the next generation of skin cells
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2009 Although Archaea are thought not to have glutamate cysteine ligase (GshA) or glutathione synthase (GshB), key enzymes in glutathione synthesis, there is a report of a putative gamma-glutamylcysteine ligase (GshA) from the archaea Methanosphaera stadtmanae (che in realta' sembra piu' moderno dell'omologo umano) GGT5_HUMAN Functioni Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione-S-conjugate such as leukotriene C4 (PubMed:21447318)
When you simply can't eat much: Liquid nutrition: protein shakes, smoothies with fruit/greens/protein powder Nutrient-dense small meals: focus on protein and vegetables in small portions Don't skip meals entirely: even a small protein shake is better than nothing Eat on a schedule: don't wait for hunger cues that may not come Need more protein strategies