Evaluating Long-Term Safety and Understanding Possible Side Effects Safety is one of the most common concerns patients bring up when considering GLP-1 medications
Mol Aspects Med (2009) 30:4259
Patient selection considerations include: Adults with BMI 30 kg/m or 27 kg/m with weight-related comorbidities [1] [7] Contraindications must be carefully reviewed, including personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 History of pancreatitis, gallbladder disease, severe gastrointestinal disease, or renal impairment requires caution Not recommended during pregnancy or lactation Clinicians should counsel patients that while inflammatory marker improvements have been observed in research settings, Zepbound is prescribed for weight management, not inflammation treatment
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Foa PP, Galansino G, Pozza G
The increasing prevalence of DM, ASCVD, and CKD necessitates therapeutic strategies that are not only effective and safe but also accessible and scalable
