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[28] Oxytocin binds to the G-protein-coupled oxytocin receptor (OXTR), activating phospholipase C, increasing intracellular calcium, and triggering downstream MAP-kinase and PI3-kinase cascades

too little may simply be less effective

= 1.2) in the placebo group

People with excess weight face a higher risk of diabetes and hypertension, which are two factors known to worsen kidney function