Inhibition of ASCT2-mediated GLN uptake in human cells using a lead compound (V-9302) resulted in attenuation of cancer cell growth and proliferation, frequent cell death, and increased oxidative stress [28]
Intriguingly, sesamin also modulated other antioxidant enzymes: MPTP typically causes a compensatory rise in catalase (an antioxidant enzyme) due to oxidative stress, but sesamin pretreatment blunted this excessive catalase increase (67)
How does tissue structure influence inflammation research outcomes
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