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Both have limited data in severe hepatic impairment

Prescription management may be easier

Other GLP-1 options and their temperature profiles Tirzepatide, the dual GIP/GLP-1 agonist sold as Mounjaro and Zepbound, has similar refrigeration requirements but may have slightly different heat tolerance based on its formulation

In May, SAHPRA and the South African Pharmacy Council raided an operation accused of unlawfully producing GLP-1 medicines and seized finished products containing semaglutide and tirzepatide

Tips for managing constipation Drink plenty of fluids Gradually increase fiber intake Stay physically active Maintain a regular bathroom routine Ask your healthcare provider before using over-the-counter laxatives Contact your healthcare provider if constipation becomes severe, painful, or does not improve

Always consult a qualified healthcare provider before starting any weight loss medication