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The average window period is 26.8 days for these assays79

Transcription factor activity changes: GHK-Cu modulates activity of key transcription factors including NF-B (inflammation master regulator), AP-1 (stress response), Nrf2 (antioxidant response element activator), p53 (cell cycle and apoptosis regulator)

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( a ) Schematic and representative images illustrating generation of 5FU resistant AKP organoids by continuous culture in increasing concentrations of drug, images at 4x magnification with mean organoid diameter denoted