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Overexpression of Nrf2 has been recently found in acute myeloid leukaemia (AML) and is associated with genomic instability, gene mutation burden and drug resistance [69]

Evidence for a role for oxidative stress in schizophrenia includes studies reporting reduced glutathione blood levels [9], reduced post-mortem glutathione concentrations [10, 11], and genetic evidence implicating schizophrenia-related polymorphisms in genes involved in glutathione synthesis [12]

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Certain other nutritious foods or specific nutrients can support higher glutathione levels and reduce the chances of glutathione deficiency