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2013, no statistically significant changes in IGF-1 or fasting glucose were detected versus placebo

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A meta-analysis involving 6,078 subjects revealed that both systolic and diastolic blood pressure were elevated in patients with PCOS compared to non-PCOS individuals, with a more pronounced increase observed in those with a body mass index (BMI) of 2530 kg/m 2 (Zhuang et al., 2022)