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Thus, damage to mitochondrial DNA and loss of can further increase ROS production, thereby creating a cycle of dysfunction that includes increased ROS production by the respiratory chain, activation of signal transduction pathways, and potentially, leading to apoptosis or necrosis, as well as the release of cytochrome c, which triggers apoptosis

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Elevated Sod2 activity augments matrix metalloproteinase expression: evidence for the involvement of endogenous hydrogen peroxide in regulating metastasis

And they were rare and they were identified typically at birth

J., Federico, J., & Palacio, C

Phlogacanthus genus: bridging traditional medicine and modern pharmacology