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Skin whitening treatments are meant for individuals having uneven skin tone, hyperpigmentation, or dark spots caused by aging, sun damage, or hormonal changes

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Topical cosmetic use is well established and generally well tolerated, but GHK-Cu is not a drug and has not been approved to treat any medical condition

Remarkably, the upregulation is observed after initial decrease in the five thiamine/ThDP-dependent proteins 1 month after the bypass (Figures 4A, 5A)