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Mention that it is related to epithalamin but is not the same as crude pineal extract

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Additionally, in SH-SY5Y cells, melatonin increased levels of Peptidyl-Prolyl cis-trans Isomerase NIMA-Interacting 1 (Pin1) [125], which has been shown to mitigate tau phosphorylation and aggregation [126]

Consistent with this, AMPK deletion decreases the activation of AKT and promotes M1 macrophage polarization [89]

Comprehensive investigations should also explore EGCGs therapeutic potential across diverse demographic groups, considering age, genetic variations, and distinct neurological disease progression patterns