Annals Of Internal Medicine 2024, 177: 1499-1508
545 For example, pelacarsen, an Lp(a) ASO drug developed by Ionis in collaboration with Novartis AG, effectively lowers Lp(a) levels by selectively cleaving Apo(a) gene (LPA) mRNA
4,5 Despite these advantages, concerns about potential adverse effects, including gastrointestinal intolerance and possible cardiovascular adaptations that may influence bone health, warrant further investigation
Your surgeon will talk with you before your surgery so you know what to expect
KPV introduces additional considerations
David Carmouche, chief medical and commercial officer at Lumeris.