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Although multiple pathways are involved in mediating tissue damage, including the polyol pathway, advanced glycation end product formation, protein kinase C activation, and the hexosamine pathway, a common feature is increased oxidative stress marked by elevated levels of reactive oxygen species (ROS) (1)

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6.2.2 Plants contribute to immune modulation in vitiligo management Anti-inflammation refers to the paraphernalia of substances that reduce swelling or inflammation (Khan et al., 2019)

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These are most effective as complements to professional treatment rather than standalone interventions for significant alcohol use disorder

2025;25(1):275 Helleberg J