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Why Are They Always Used Together

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Cartilage tissue engineering involves seeding cells on a scaffold to support tissue growth and phenotypic maintenance by regulating growth factors and producing engineered cartilage with structures and functions equivalent to those of natural tissue [45, 46]

The safety implications of receptor desensitization include possible changes in the dose-response relationship over time and the possibility that higher doses may be needed to achieve similar effects in long-term protocols

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