Because of the enigma of AD molecular mechanisms, there is an urgent need for alternative therapies acting on multiple biological pathways (Wu et al., 2024)
However, the downregulated proteins exhibited enrichment in metabolic pathways, particularly the catabolic process ( p adjusted = 0.0011), cellular catabolic process ( p adjusted = 0.0006), and cytoplasmic translation ( p adjusted = 3.2E-07) (Supplementary Figure S6C
There, they help filter blue light and act as antioxidants, protecting retinal tissues from oxidative stress and light-induced damage
The expression of NF-B, iNOS, and VEGF proteins was significantly reduced in the group treated with soybean compared to that in the disease group
Caution: May interact with alcohol intake and poor diet patterns that affect antioxidant balance
The SURMOUNT-2 and STEP-2 trials both showed this pattern 3,4