revealed that the nuclear membrane-localized circular RNA circ-calm4 plays a crucial role in regulating ferroptosis in hypoxia-exposed PASMCs
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[DOI] [PubMed] [Google Scholar] Ghezzi P, Di Simplicio P
Ethics declarations Conflict of interest The authors declare they have no conflicts of interest
The efficacy and safety of -nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: A randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial
The impaired cross-talk between dysfunctional endothelial cells and fibroblasts further compromises angiogenesis, as endothelial cells provide critical paracrine signals (such as PDGF-BB) that recruit and activate fibroblasts, while fibroblasts produce VEGF and deposit the ECM scaffold necessary for endothelial tube formation