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"For the first 38 years of my life, I was overweight - now I'm six stone (38kg) lighter," says Tanya

1 This approach is designed to be sustainable after medication stops, because it doesnt rely on a tracking system you might abandon

The dose-escalation principles established for licensed incretin therapies (as described in the EMC summaries of product characteristics for Wegovy and Mounjaro) also inform how titration is managed within retatrutide trials

However, it is noteworthy that 20% of patients treated with the 2.4 mg dose of pemvidutide discontinued treatment due to adverse events, with nausea and vomiting being the most common AEs