Together, miRNAs drive mitochondrial metabolic reprogramming in CRC by modulating energy production, redox homeostasis, and tumor microenvironment responses to stress
the activity of the enzymes that we evaluated is associated with the increase of inorganic nutrients, such as selenium, zinc, magnesium, and iron
It is primarily metabolized via glucuronidation and mitochondrial beta-oxidation, usually with a minor contribution from CYP2C9 and CYP2C19
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5-OP accumulation does not inhibit the Chac1 enzyme The accumulation of 5-OP induces a general stress response in cells, yet the initial steps triggering this response remain unclear, as 5-OP itself appears an inert molecule
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