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[DOI] [PMC free article] [PubMed] [Google Scholar] Cordeira J.W., Frank L., Sena-Esteves M., Pothos E.N., Rios M

In a study conducted in individuals with metabolic syndrome without diabetes or cerebrovascular event, liver enzymes and ultrasound improved during the study with the use of statins 37

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Researchers interested in advancing this work must first establish pharmacokinetics in human subjects before any efficacy claims can be made

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Abstract Although most patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) receiving CD19-targeted chimeric antigen receptor (CAR) T cell therapy achieve remission, loss of CAR T cell functionality and subsequent relapse remains an unmet therapeutic need