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In our experience, most people who take Accutane have an improved mood (Accutane may act as an antidepressant for people who are devastated by their acne)
Baumeister et al., 2016
(BSH B12 Deficiency / PA Diagnostic Flowchart) onlinelibrary.wiley.com/doi
Finally, G6PD may play a role in immunosenescence, given that G6PD activity in lymphocytes declines with age (114, 115)