[2,4] This is the period in which people can become falsely reassured
As long as 72 or more hours have passed, you can inject at whatever local time is convenient
Studies show an average reduction of up to 20% in body weight when combined with lifestyle changes
Fewer than 5% of clinical trial participants discontinued treatment specifically due to GI adverse events, suggesting that the vast majority found their symptoms tolerable over time
NICE guidelines recommend a stepwise approach including NSAIDs for pain relief, hormonal therapies (combined oral contraceptive pill, progestogens, or LNG-IUS), GnRH analogues for severe symptoms, and laparoscopic surgery when medical management is insufficient or fertility is a priority
This is much greater than the pain reduction in another recent study among people with obesity and knee osteoarthritis