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IV glutathione has FDA approval as an adjunct for cisplatin chemotherapy protection in cancer treatment

doi: 10.1016/j.biopha.2016.05.046 193 KhajaviniaAVarshosazJDehkordiAJ

10.1002/jcp.29232 J

The mechanism involves upregulation of VEGF expression a key growth factor in new blood vessel formation and activation of ERK1/2 signaling pathways that drive cell proliferation, migration, and angiogenesis

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After 11 months, the retinas of the rats were evaluated for changes in blood vessels, cellular damage and other retinal changes characteristic of diabetic retinopathy