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Peri-articular muscle biopsies in OA demonstrate fiber-type atrophy (especially type II fast-twitch fibers), increased infiltration by adipocytes and macrophages, fibrosis, and mitochondrial abnormalities

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To our knowledge this is the largest and the only prospective study up to now which has investigated the association of apoA-IV with cancer, independent whether the literature in CKD or non-CKD patients is considered (Graphical Abstract)

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