This approach refines observed associations, confirms their mechanistic plausibility, and identifies the most promising targets for preclinical and clinical testing (Turjeman et al., 2025)
Aliquot and label divide into single-use portions
GLP-1RAs also reduced several other markers of oxidative stress in rodent stroke models, such as blood and brain ROS counts, blood levels of derivatives of reactive oxygen metabolites (d-ROMs), and brain levels of dihydroethidium, a marker of ROS production [66, 87]
PMID: 42070571
The results indicate that similar to semaglutides reduction in food cravings to aid weight loss, the desire or craving for alcohol may also be weakened
Considering the MM specific SF3B1 hotspot mutation in R625, developing strategies that can specifically target R625 mutant SF3B1 might may achieve benefit MM patients with low side effects