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When administered as AXS-05, the accumulation ratios of dextromethorphan based on maximum plasma concentration ( C max ) and area under the concentrationtime curve (AUC 012 ) are 20 and 32, respectively, compared with 1.3 based on C max and 1.4 based on AUC 012 for dextromethorphan alone [103]

These products were found with a reduced energy than the corresponding starting materials, indicative of an energetically favored catalytic transformation

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During the process it was painless and calming energy

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10.1242/jcs.00930 J Cell Sci