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It markedly reduces ROS and malondialdehyde (MDA) levels, restores glutathione balance, and up-regulates the expression of Nrf2 and its downstream effector HO-1

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The most common gastrointestinal side effects include nausea (very common, affecting 1/10 patients), diarrhoea, vomiting, abdominal pain, and decreased appetite

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Clearance was determined by nonlinear regression analysis for k e and t[/ 2 and the equation Cl, nt = k e Vd

And in the third, blood glucose levels were lower (by a modest 5 percent) in the Eriomin takers than in the placebo takers