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VT-464: A novel, selective inhibitor of P450c17(CYP17)-17,20 lyase for castration-refractory prostate cancer (CRPC) [abstract]

doi: 10.3389/fendo.2025.1587891 Received 05 March 2025 Accepted 24 June 2025 Published 16 July 2025 Volume 16 - 2025 Edited by Lawrence Merle Nelson, Mary Elizabeth Conover Foundation, Inc., United States Reviewed by Roger Smith, The University of Newcastle, Australia Qinqin Gao, First Hospital of Soochow University, China Updates Copyright 2025 Anti, Gheorghe, Deming, Adeoye, Zhang and Mata-Greenwood

Compounding caution: The FDA has flagged unapproved or fraudulent GLP-1/tirzepatide products sold online

200 ng/mL GHK-Cu in plasma at age 20 10% regrowth 407.5 SALT score drop dramatic improvement 0 adverse events no scarring or infection The study also pioneered the use of AI (ChatGPT) for outcome evaluation finding it aligned within 7.5% of blinded dermatologist assessments

Total glutathione values obtained in the DMg250 (45.68 9.67 ng/l) and DI (36.76 3.99 ng/l) treatment groups showed a 49.2% and 19.9% increase respectively compared to the DU group (Table 2)

3e, Huh7, Hep3B, and HepG2)