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It is possible that as the soma size increases, GABA is released aggressively from the astrocytes which would cause drop in astrocytic GABA levels as another study reported a decrease in memory function of mice was due to excessive GABA production by astrocytes around amyloid plaques [102] Thanks to the studies aiming to illuminate the pathologic mechanism several drugs that are targeting the various GABAergic mechanisms

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Proc Natl Acad Sci USA 2008, 105: 74107415

& Meinl, E

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