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Owing to their high oxygen consumption, skeletal muscle fibers are inherently prone to ROS generation during contraction and metabolism (Kann et al., 2022)

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[66] Despite off-label prescriptions being a normal and legal occurrence in medicine, in 2015 the Drug Enforcement Administration of the US Department of Justice published a position considering off-label prescriptions of HGH to be illegal, and to be a key path for illicit distribution of HGH

Zhang D-W, Shao J, Lin J, Zhang N, Lu B-J, Lin S-C, et al