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Fathi E, Farahzadi R
In vivo and in vitro models, it was found that in the IDH1 mutant glioma cells intervened by triptolide, the transcriptional activity of Nrf2 was suppressed, and the expression of genes related to glutathione anabolic metabolism (GCLC, GCLM, and SLC7A11) was significantly down-regulated
THE FOUNDATION OF HEALTHY AGING: Cellular energy powers every organ and system in the body
270 In pancreatic adenocarcinoma, XBP1s promotes angiogenesis through VEGF-independent mechanisms, further underscoring its capacity to sustain tumor vascularization and growth
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