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10.1016/j.apsb.2022.02.003 137 TonnusW.MeyerC.SteinebachC.BelavgeniA.von MssenhausenA.GonzalezN

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For glutathione agarose, however, we dont strip the glutathione and add it back on, so regeneration in this context is more like a really good cleaning that restores the original binding capacity to the glutathione beads

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Mechanistically, the treatment simultaneously activated Wnt/-catenin and Hippo pathways while suppressing TGF- signalling via miRNA cargo, thereby coordinating anti-apoptotic and pro-proliferative gene programs [22]

That's a downside, but not a big one