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NAC is plausible on top of that

Hypoxic regions in tumors exhibit radioresistance and may upregulate alternative metabolic enzymes, reducing the radiosensitizing effects of glycolysis blockade [130]

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Giannakou, K

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When they are impaired because of nutrient deficiencies, genetic variation, or other metabolic disturbances, homocysteine levels rise, making it a clinically useful marker of impaired one carbon metabolism