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reported that PMX53, a C5a receptor 1 (C5aR-1) antagonist, mitigated hepatic IRI through inhibiting pro-inflammatory cytokine release and neutrophil/macrophage infiltration and platelet aggregation (Kusakabe et al., 2020), suggesting the crosstalk between coagulation and complement system

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Among these, a negative correlation was observed between plasma lipopolysaccharide-binding protein (LBP) levels and C4A gene copy number was observed in patients with schizophrenia, but not in healthy controls (143)