If you want to understand how stress complicates this metabolic process, check out our guide on the link between cortisol and insulin resistance
Mistake 7: stopping abruptly Discontinuing semaglutide drops cold turkey often leads to rapid appetite rebound and weight regain
Never discontinue semaglutide without medical guidance, particularly if using it for diabetes management, as abrupt cessation may affect glycemic control
The boxed-warning row is important and asymmetric: because tirzepatide is approved, its rodent thyroid C-cell finding is formally carried on the label as a warning, whereas CagriSema simply has no label yet
Allan Ryan, Editorial Director
In head-to-head trials, tirzepatide consistently outperformed semaglutide for weight loss