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A hallmark of IgAN is the accumulation of IgA-containing immune complexes in the glomerular mesangium

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A key player in the formation of invasive breast tumors is TREX1, which mediates confinement-induced DNA damage, collagen degradation, and the acquisition of a hybrid epithelial-mesenchymal phenotype [195]

SURMOUNT-1 Trial (NEJM, 2022): Tirzepatide up to 20.9% weight loss

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