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In mouse models, GLP-1R agonists have been shown to mitigate inflammation in contexts ranging from colitis to cardiovascular injury ( 5 )

HT29 cells (ATCC HTB-38) and THP-1 cells (ATCC TIB-202) were obtained from the American Type Culture Collection (ATCC)

The appeal of KPV is that it appears to retain much of -MSHs well-documented anti-inflammatory activity while shedding the pigmentation effects associated with melanocortin-receptor signaling

Invest 134, e176660

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Published research involving GHK-Cu peptides is limited to non-clinical and investigational settings that explore cellular communication mechanisms, peptidemetal interactions, and molecular signaling models