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17 March 2016

(2008) S-adenosyl-L-methionine hydrolase (adenosine-forming), a conserved bacterial and archeal protein related to SAM-dependent halogenases, ChemBioChem , 9 , 2215-2219, Hoffman, J

Int J Mol Sci 20(6):1519

Adverse effects in clinical trials were predominantly gastrointestinalincluding nausea (24-30%), diarrhea (18-23%), and constipation (16-24%) and were generally mild to moderate in severity, most commonly occurring during dose escalation

59 Ameghino, L., Farez, M

Earlier animal studies, observational research, and smaller human trials had suggested that GLP-1 receptor agonists might also influence alcohol-related behaviors, providing the rationale for this study