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Dosing, delivery method, and protocol design all require a trained eye

Assessment of injection site tolerance and any side effects experienced

Clinically, AD is characterized by progressive cognitive decline and pathologically, its two main hallmarks are intracellular neurofibrillary tangles comprised of the protein tau and extracellular -amyloid (A) plaques (Roy et al., 2023), since A aggregation has been determined as source of oxidative stress (Leng and Edison, 2020

The human efficacy and safety profile therefore remains unestablished

Cell cycle control of the human HSP70 gene: implications for the role of a cellular E1A-like function

Mice and rats were allowed one week of acclimatization and kept on a 12:12 h light/dark cycle with ad libitum access to water and standard chow