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Importantly, when polyphenols and topoisomerase II inhibitors were combined, it was possible to induce a synergistic decrease in cell proliferation (measured as ATP levels), cell-cycle arrest and induction of apoptosis in leukaemia cell lines

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Zhonghua Nei Ke Za Zhi

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J Readaptation Medicale (Elsevier Masson SAS)

Unverified anecdotal reports from online forums mention various effects, though these cannot be confirmed without proper clinical investigation and may not represent causal relationships: Unverified reports of hormonal changes : Some users mention changes in libido or sexual function, though no causality has been established Theoretical cardiovascular concerns : Based on its purported vascular effects, though no clinical evidence exists Injection site reactions : Pain, redness, or swelling when administered subcutaneously Gastrointestinal symptoms : Nausea or abdominal discomfort in some reports Unknown long-term effects : No data exists on prolonged use or cumulative toxicity A significant safety concern involves product quality and contamination